Entries by intiquan

PAGE2018-Workshop: Using R and Shiny to support efficient PK/PD and QSP modeling, parameter estimation, simulation, and reporting in Word

PAGE 2018 Meeting, May 28 Monday, 08:00-17:00 Workshop Description IntiQuan is running a full day hands-on workshop on PK/PD and QSP modeling, simulation, and parameter estimation in the open-source and freely available R environment. The major topics covered are: Morning session PK, PKPD, QSP modeling in R. Description of models and simulation Reuse of models from […]

IQRsysPharm: Systems Pharmacology Modeling and Reporting in R, powered by Shiny

>>> Try it out – here <<< Background: Quantitative Systems Pharmacology (QSP) gains more and more attention in the Pharmacometric Community. Models in this area are often far more complex than typical PK/PKPD models, traditionally used in Pharmacometrics. Modelers in this field are often faced with the fact that none of the typically used pharmacometric tools […]

Tight project timelines require an efficient reporting system

In many scientific and technical environments reports need to be written. Often a large number of figures, tables, text files, in-line text, and numerical values need to be added. Reporting is often complicated by the corporate requirement to use Word as software for report writing, leading to scientists having to copy and paste figures and […]

Leverage SBML models for modeling in Quantitative Systems Pharmacology

Systems Pharmacology gains in interest in the Modeling and Simulation community. Thus does also the Systems Biology Markup Language (SBML), in which many systems pharmacology type of models are coded (see, e.g. Biomodels Database). SBML, however, is very badly supported when using R. Some packages (such as SBMLR) are available and claim to be able to […]

Internship for R Programmer

Basel, Switzerland IntiQuan is seeking an R programmer for an Internship position of 3-6 months. Overview Increased demand for support of model-based drug development through pharmacometric and systems pharmacology type of analyses requires tools that meet requirements regarding user-friendliness, flexibility, efficiency, compliance, and state of the art methodology. It can be argued that there is […]

Modeling and Simulation Scientist

Basel, Switzerland IntiQuan is seeking a modeling and simulation scientist to join our team in 2017. Overview Qualified individuals will contribute to fighting diseases through collaborations with our customers in biomedical research and development for new drugs and diagnostics. M&S scientists will be expected to develop and implement quantitative, data-driven strategies for knowledge integration and decision […]

Version 1.2.1 of IQM Tools available for download

A new public version of IQM Tools is available for download. Please refer to the IQM Tools website for more information. Version history (note that the previously public available version was V1.0). Version 1.2.1 (30.04.2016) ———————— – Minor big fixes Version 1.2 (13.04.2016) ———————— – Allow non-numeric lag time definitions in IQMdosing schemes – Ensured […]

ACoP7-Workshop: Industrialization and Knowledge Management of Pharmacometric Analyses

ACoP7 Meeting, October 23rd Sunday, 08:00-17:00, Hyatt Regency, Bellevue, WA, US Workshop Description Pharmacometric analyses have become an integral part of drug development and the decision making process across the pharmaceutical industry. Even though, many of the pharmacometric analyses are fairly similar in nature, there is a large heterogeneity in the planning and conduct of […]

Introductory course in “Modeling & Simulation in the Pharma Industry” at the ETH Zürich – Spring 2016

The goal of pharmacometric modeling and simulation in the pharmaceutical industry is to provide an integrative and quantitative view of available knowledge and current status of a drug development project to support development of a compound and facilitate the decision making process on dose selection. This course gives an introduction to drug development and its […]