IQR Tools

Integrated solution for seamless and efficient
modeling across systems biology, systems
pharmacology
and pharmacometrics

IQR TOOLS

Increased demand for support of model-based pharmacometrics and systems pharmacology analysis requires user-friendliness, flexibility, efficiency, compliance, and state-of-the-art methodology. IQR Tools enables a seamless access to pharmacometrics parameter estimation tool, such as NONMEM, MONOLIX, and NLMIXR. In addition, it provides a world-leading powerful estimation method for systems pharmacology type of modeling. Important other features are the seamless integration of optimal experiment design and NCA functionality.

CROSS-DISCIPLINE

Making bridges between systems biology, systems pharmacology, and pharmacometrics under one single platform. Facilitates QSP, NCA, PBPK, PKPD, time-to-event, and joint modeling.

USER-FRIENDLY

Well documented, with shallow learning curve. Allows for fluent use of NONMEM, MONOLIX, and NLMIXR, without the need for syntax expertise in each tool.

COMPLIANT

Built-in traceability promotes required regulatory compliance and facilitates reproducibility of analyses. Integration with reporting allows for traceability of analyses from data-to-report.

FEATURES

Model Analysis

Simulation

Sensitivity

Dosing Descriptions

Experiment Descriptions

Data Analysis

Graphical Exploration

NCA

Summary Tables

Data Checking

Parameter Estimation

NONMEM

MONOLIX

QSP

NLMIXR

NLME TooTs

Bootstrap

VPC

Covriate Search

Time-to-Event & Joint Modeling

Clinical Trial Simulation

Sampling Individual Parameters From NLME Models

Population Characteristics

Optimal Experiment Design

Evaluation of Scenarios

Optimization of Scenarios

Workflows

PopPK Workflow

PopPK/PD Workflow

Reporting

Markup Language

DOCX

Packaging of Submission Data (XPT, define.pdf)

Standard data format

Intuitive mathematical model representation

Get inspired how IQR Tools can help you in your projects

Additional Information

TECHNICAL REQUIREMENTS

  • Supported R Versions: 3.3.0 -> latest R version on MRAN
  • Supported operating systems: Windows, Linux, Mac 

AVAILABILITY

  • Free for Academic users, Non-profit organizations, Government agencies, IntiQuan clients
  • Other users and organizations can ask for a quote at info@intiquan.com  

DOWNLOAD & INSTALLATION

For download, installation instructions, and documentation visit the IQR Tools repository page

Ready to step-up your modeling & simulation game?