Increased demand for model-based pharmacometric and systems pharmacology analyses requires user-friendliness, flexibility, efficiency, compliance, and state-of-the-art methodology. IQR Tools enables seamless access to pharmacometrics parameter estimation tools, such as NONMEM, MONOLIX, and NLMIXR. In addition, it provides a world-leading powerful estimation method for systems pharmacology type of modeling. Important other features are the seamless integration of optimal experiment design and NCA functionality.
Making bridges between systems biology, systems pharmacology, and pharmacometrics under one single platform. Facilitates QSP, NCA, PBPK, PKPD, time-to-event, and joint modeling.
Well documented, with shallow learning curve. Allows for fluent use of NONMEM, MONOLIX, and NLMIXR, without the need for syntax expertise in each tool.
Built-in traceability promotes required regulatory compliance and facilitates reproducibility of analyses. Integration with reporting allows for traceability of analyses from data-to-report.
Model Analysis
Simulation
Sensitivity
Dosing Descriptions
Experiment Descriptions
Data Analysis
Graphical Exploration
NCA
Summary Tables
Data Checking
Parameter Estimation
NONMEM
MONOLIX
QSP
NLMIXR
NLME TooTs
Bootstrap
VPC
Covriate Search
Time-to-Event & Joint Modeling
Clinical Trial Simulation
Sampling Individual Parameters From NLME Models
Population Characteristics
Optimal Experiment Design
Evaluation of Scenarios
Optimization of Scenarios
Workflows
PopPK Workflow
PopPK/PD Workflow
Reporting
Markup Language
DOCX
Packaging of Submission Data (XPT, define.pdf)
Standard data format
Intuitive mathematical model representation
For download, installation instructions, and documentation visit the IQR Tools repository page
